Some Chinese Herbs and Their Injectible Functions

Ai Ye (Fo. Artemisiae Argyi)

  • Ampoule (2 g of crude drug): 4-6 ml IM daily

  • Indications: chronic hepatitis and viral myocarditis.

Bai Hua She She Cao (Hb. Hedyotis Deffusae)

  • 2 ml containing 4g of crude herb: 1-2 ampoules IM qd or bid.

  • Indications: None functions attributed to the IM specifically, see decoction functions.

Ban Lan Gen (Radix Isatidis)

  • No protocols provided. [1]

Ban Mao (Mylabris)

  • Cantharidin ampoule: .25 mg gradually increased to 2 mg IM once daily, 1-3 months as 1 course.

  • Indications: none noted in source text.

  • Caution: All preparations of Chinese blister beetle are strong poisons, which may cause nephritis, cystitis, burning sensation of digestive tract, vomiting, palpitations and numbness of fingers. It is contraindicated in cases with cardiac, renal and gastrointestinal diseases, and should be taken after meals. Toxicity and side effects may be ameliorated if the drug is taken with green tea, diuretics, or stomachics.

Bu Gu Zhi (Fr. Psoraleae)

  • Psoralen ampule: 1-2 ml IM qd.

  • Indications: for leukoderma and psoriasis.

Chai Hu (Rx. Bupleuri)

  • 3-5 ml IM 1-2 times daily for fever.

  • Indications: none noted in source text.

Chan Su (Venenum Bufonis)

  • Resibufogenin ampoule (1 ml containing 1 mg): 2 mg added in 10% glucose solution 20-40 ml IV slowly for cardiovascular diseases. Pharmacological actions: 1) Cardiotonic effect similar to digitalis. 2) Exciting effect on CNS. 3) Local anesthetic effect of bufalin is 30-60 times that of cocaine. 4) Inhibiting leukemia and Ehrlich-Ascites tumor in vitro.

  • Cautions: overdose may cause nausea, vomiting, diarrhea, even general paralysis. LD50 is 41 mg/kg in mice. The toxic symptoms include shortness of breath, arrhythmia, paralysis, or even death.

Chang Chun Hua (Hb. Catharanthi Rosei)

  • Vinblastine ampoule: 5-10 ml added in normal saline 10 ml IV once every 7-10 days, 50-80 mg as one course. Vincristine ampoule: 1-2 ml added in normal saline 20 ml IV once a week, 10-20mg as one course.

  • Pharmacological action: Vinblastine and vincristine are the active components which inhibit leukemia and other cancers. They interfere with mitosis and inhibit leukemia and other cancers. They interfere with mitosis and inhibit synthesis of purine, DNA, and RNA.

Chuan Xiong (Rz. Ligustici Chuanxiong)

  • Tetramethylpyrazine injection: 40-120 mg added in glucose solution IV in drips daily.

  • Indications: angina pectoris and ischemic apoplexy.

Dan Shen (Radix et Rhizoma Salviae Miltiorrhizae)

  • No protocols provided. [1]

Dang Gui (Rx. Angelicae Sinensis)

  • 5%-10% ampoule 2-4 ml IM 1-3 times daily: Point injection: 0.5-1.0 ml for 1 point, 2-4 points for 1 time, once daily.

  • Indications: none noted in source text.

Dong Ling Cao (Hb. Rabdosiae Rubescentis)

  • 75-100 mg in glucose solution IV for drips qd or qod, totally 1-3g.

  • Indications: cancer.

E Zhu (Rz. Zedoariae)

  • 5% Oleum Zedoariae Ampoule: 5-10 ml topical injection qd for carcinoma of the cervix. 1% Curcumenol Ampoule: 2-4 ml topical injection qd for carcinoma of cervix. 30% Zedoariae Ampoule: 100-300 ml IV for drips qd for various kinds of tumors.

  • Indications: carcinoma of cervix and various kinds of tumors as described above.

Fen Fang Ji (Rx. Stephaniae Tetrandrae)

  • Ampoule (Hanfangchin A 60 mg): 120 mg added in normal saline 20 ml IV daily, or 30-60 mg IM bid.

  • Indications: none noted in source text.

Hong Hua (Flos Carthami)

  • 50% solution 2-4 ml IM once or twice daily; 10-15 ml added in 10% glucose 250 ml IV for drips daily, 15-20 times as 1 course.

  • Indication: ischemic apoplexy.

Hua Qian Jin Teng (Rx. Stephaniae Sinicae)

  • Ampoule (containing chinensin): 1.0-1.5 mg/kg IV as muscle relaxant.

  • Indications: for restoration of fracture and surgical operation.

Hua Sheng Yi (Testa Arachidis Hypogaeae)

  • Ampoule (injection fo testa Arachidis Hypogaeae): 2-4 ml IM once or twice daily.

  • Indications: bleeding syndromes.

  • Pharmacological action: Inhibits fibrinolysis, promotes thrombocytopoiesis and shortening the bleeding time.

Huang Qi (Rx. Astragali seu Hedysari)

  • 100% Atragali ampoule 2 ml IB bid.

  • Indications: none noted in source text.

Huang Qin (Rx. Scutellariae)

  • Ampoule (containing baicalin 60 mg in 2 ml): 1-2 ampoules IM 1-2 times daily, or 8-20 ml in 10% glucose 500 ml IV for drips daily.

  • Indications: none noted in source text.

Kong Xin Lian Zi Cao (Hb. Alternantherae)

  • 500-1000g of crude drug decocted into solution for oral use or 500% solution for IV mixed with 10% glucose solution in drips, with a dose of 20g/kg, the maximum dose should be less than 1000g

  • Indications: for encephalitis B and epidemic hemorrhagic fever:

Ku Gan Cao (Hb. Sophorae Alopecuroidis)

  • Sophocarpine ampoule: 0.2-.4 g added in glucose solution IV for drips daily, 10 days as 1 course, continuing for 2 months with a 5-day interval between two courses.

  • Indications: malignant hydratidiform mole, chorionic epithelioma and leukemia.

Lun Huan Teng (Rx. Cycleae Barbatae)

  • Ampoule: Its alkaloid 0.8-1.0 mg/kg, or chloro-methyl-levocurare 0.2-0.3 mg/kg IV.

  • Indications: muscle relaxant for restoration of fracture. This applies to both of the substances described above.

Mao Dong Qing (Rx. Ilicis Pubescentis)

  • Injectio Ilicis Pubescentis 2-4 ml IM 2-4 times daily; Injectio Ilicin A 20 mg added in glucose solution IV in drips.

  • Indications: ischemic apoplexy. (source text does not indicate whether or not both techniques apply to ischemic apoplexy)

Nong Ji Li (Hb. Crotalariae)

  • Monocrotaline ampoule (2ml containing 50 mg): 1 ampoule injected to the base of the tumour daily, 15 days as 1 course, the second course may be continued after 3-5 days interval.

  • Pharmaceutical actions: monocrotaline is an anticarcinogenic component which inhibits the synthesis of DNA and RNA.

Qi Ye Liang (Rx. Schefflerae Arboricolae)

  • 2 ml IM 1-3 times daily.

  • Pharmacological actions: 1) Analgesic for abdominal and bliary colics, and trigeminal neuralgia, 2) Sedative, 3) Antispasmodic for bronchial asthma and asthmatic bronchitis.

Qian Gui Gian Jin Teng (Rx. Stephaniae Dielsianae)

  • 1 ml containing 15 mg of total alkaloid: 0.15-0.4 ml/kg added in 5% glucose 20 ml IV.

  • Indications: muscle relaxant for abdominal operation.

Qing Hao (Hb. Artemisiae Annuae)

  • Ampoule (2 ml containing 100 mg of volatile oil): 200 mg IM stat, 100-200 mg IM 6-8 hours later and in the second and third day.

  • Indication: malaria.

San Jiang Shan (Ramulus et Folium Cephalotaxi Fortunei)

  • Harringtonine injection: 1-6 mg added in 5-10% glucose 500 ml IV for drips daily, 5-7 days as one course, 1-3 courses may be applied at an 1-2 week intervals; homo-harringtonine, same dosage as harringtonine.

  • Indications: this herb is mainly used as an anticarcinogenic for acute non-lymphocytic leukemia such as acute myelocytic leukemia, acute monocytic leukemia, malignant lymphoma.

  • Pharmacological action: 1) Harringtonine, homo-harringtonine, iso-harringtonine and deoxy-harringtonine are the anticarcinogenic components, which interfere the cell growth and mitotic activity, damage and inhibit the growth of S-stage cells and inhibit the synthesis of DNA. Harringtonine and homo-harringtonine are more effective for the interference of mitotic activity. 2) Inhibiting the hematopoeitic cells in bone marrow. 3) causing irritant effect on digestive tract.

Sang Ji Sheng (Rm. Taxilli)

  • Ampoule (5ml containing 10g of crude drugs): 10 ml added in 50% glucose 20 ml IV once daily.

  • Indications: none noted in source text.

Shan Ci Gu (Bulbus Iphigeniae)

  • Clochincine amide 10 mg: 10 mg IV for drips daily, total dosage 0.2-0.3g. This herb may cause nausea, vomiting, general pain, palpitation, alopecia, etc. or even leukocytopenia, so the dosage should be limited.

  • Pharmacological action: Clochincine, one of its active components, and tis derivatives exerts an inhibiting effect on various kinds of sarcoma and parenchymatous liver cancer in experimental animals. It serves as inhibitor in the intermediate stage of cellular mitosis.

Shi Chang Pu (Rz. Acori Graminei)

  • 2 ml containing 10 mg of volatile oil: 2-4 ml IM 2-6 times a day; or 16-20 ml added in 10% glucose solution 500 ml IV for drips 1-2 times a day.

  • Indications: pulmonary encephalopathy and encephalitis.

Shi Nan Teng (Rm. Wallichii seu Puberulii)

  • 2 ml containing 8g of crude drugs of Wallichii): 2 ml IM once or twice daily; or 4-8 ml added in 10% glucose solution 500 ml IV for drips. Wallichii.

  • Indications: angina pectoris, cerebral thrombosis and embolism.

Shi Shang Bai (Hb. Selaginellae Doederleinii)

  • 2 ml containing 10g of crude herb: 1 ampoule IM tid or 14-20 ml added in glucose solution IV for drips once daily.

  • Indications: none noted in source text.

Si Ji Qing (Fo. Ilicis Chinensis)

  • 4 ml IM bid.

  • Pharmacological actions: active components such as protocatechuic acid and protocatechuic aldehyde possess broad-spectrum antibacterial effect, especially on Staphylococcus arueus.

Tao Ren (Sm. Persicae)

  • 100% solution, 2 ml IM daily for diseases of fundus aculi; 1 ml postocular injection every other day, 10 times as 1 course.

  • Indications: none noted in source text.

Teng Huang (Resina Garciniae)

  • Ampoule: 100-200 mg added in normal saline 20 ml IV.

  • Indications: carcinoma of breast, cervix and pancreas and malignant lymphoma.

  • Pharmacological actions: Morellic acid, one of its components, inhibits Ehrlich-Ascites tumor and sarcoma 180. Inhibits BEL-7402 species of hepatic cancer cells and HeLa cells in vitro. Increases white blood cells and promoting its phagocytosis during the treatment of cancer in experimental animals.

  • Caution: local pain and phlebitis may occur at the site of injection.

Tian Hua Fen (Rx. Trichosanthis)

  • 10 mg of trichosanthin added in physiological saline 500 ml IV for drips, once 5-7 days after test.

  • Indications: trophocytic tumor and labor induction.

  • Cautions: intravenous injection may cause fever and allergic reaction, or even allergic shock in severe cases, which can be alleviated by preceding use of corticosteroids. Bed rest for 1-2 days is necessary after injection. Contraindicated for those patients suffering from liver, heart, and kidney diseases, severe anemia and psychosis.

Wu Tou (Rx. Aconiti)

  • Ampoule (2ml containing 100 mg of aconitine): 2-3 ampoules added in 5% glucose 500 ml IV for drips daily, or 1 ampoule IM daily or bid.

  • Indications: none noted in source text.

  • Caution: Aconitine is a poison which can be detoxified by high temperature. Its toxicity varies with the variety, its habitat, process of preparing, dosage, constitution of the patient, pathological state (increased tolerance in patients with yang-deficiency, and descreased in those with yang-hyperactivity), climate (more liable to be poisoned when the temperature is over 20C), and the accompanied usage of drugs (antagonized by Jiang (Rz. Zingiberis and Gan Cao Rx. Glycyrrhizae, and synergetic with Ma Huang Hb. Ephedrae)

  • Indications: none noted in source text.

Xi Sheng Teng (Hb. Cissampelotis)

  • Cissampareine II ampoule: 0.25-0.4 mg/kg IV.

  • Indications: muscle relaxant for restoration of fracture.

  • Pharmacological Action: Its component cissampareine can: 1) block the autonomic ganglia, release histamine to cause hypotension. 2) Relax striated muscles. 3) Exerting cardiotonic effect on rabbits and frogs in vitro. 4) Stimulating the ileum of guinea pigs in vitro. 5) Inhibiting the cells of nasopharyngeal carcinoma in vitro.

  • Cautions: overdosage of cissampareine II may cause respiratory failure, or even apnea.

Xi Shu (Fr. seu Rx Camptothecae Acuminatae)

  • Camptothecinum injection: 5 mg IM, bid or 15-20 mg added in normal saline 20 ml IV, once every other week, 200-250 mg as one course; 20 mg bladder perfusion twice a week or 5-10 mg intracancerous injection qod for bladder cancer. Camptothecinum suspension: 2.5-5.0 mg in 50% glucose 40 ml IV once every week, 50-100mg as one course, maintenance dose 2.5 mg every week, for liver cancer, leukemia and lymphoma. Hydroxycamptothecimum injection: 4-10 mg added in normal saline 20 ml IV qd or qod, 60-120mg as one course.

  • Indications: bladder cancer, liver cancer, leukemia and lymphoma as indicated above.

  • Pharmaceutical actions: Hydroxycamptothecine is an anticarcinogenic which inhibits polymerase of DNA or damages DNA directly.

Ya Dan Zi (Fr. Bruceae)

  • 10% oleum ampoule: 2-4 ml IM or topical injection once daily.

  • Indications: Local injection for cancer of cervix, and mammary cancer; intramuscular injection for tumor of the digestive tract, cancer of cervix and lung.

  • Caution: Cases with peptic ulcer, gastritis, poor liver function and kidney function are contraindicated.

Yu Xing Cao (Hb. Houttuyniae)

  • Decanoyl acetaldehyde solution 10 mg IM bid.

  • Indications: for pelvic inflammation, chronic adnexitis, endometriosis, vaginitis, pneumonia. D.A. is bacteriostatic and fungistatic.

Yun Zhi (Polystictinum)

  • Ampoule (containing 40 mg of its polysaccharide): 1 ampoule IM bid, 4 weeks as one course, another course may be continued after an interval of 2 weeks; or 3-4 ampoules added in 10% glucose solution 300 ml IV for drips daily for 10 days, and then continue for 10 days after an interval of 1-2 weeks.

  • Indications: none noted in source text.

Zhang Ye Ban Xia (Rz. Pinelliae Pedatisectae)

  • Ampoule (2 ml containing 10-20g of crude drug): 1 ampoule IM once daily or bid;

  • Indications: local injection for cancer of cervix.

Zhi Shi (Fr. Aurantii Immaturus)

  • For shock, 10-40 g IV, followed by 20-100 g IV in drips.

  • Indications: none noted that are unique to injectable.

Zhong Jie Feng (Hb. Sarcandrae)

  • Ampoule (2 ml containing 10g of crude herb): 2-4 ml IM or IV bid or tid.

  • Indications: none noted in source text.

Zhu Ling (Polyporus Umbellatus)

  • Ampoule (containing its polysaccharide): 40 mg IM once or twice daily.

  • Indications: may be used together with chemotherapy and radiotherapy for cancers of the lung and liver and acute leukemia.

Zi He Che (Placenta Hominis)

  • No protocols provided. [1]

Sources:

    1. Therapeutics of Acupuncture and Moxibustion. Shi Min (Ed.) Medicine & Health Publishing Co. Hong Kong, 1996. ISBN: 962-300-079-0

    (all others) Chinese-English Manual of Common(ly)-Used (Herbs) in Traditional Chinese Medicine ISBN: 7-5359-0871-3

        

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